Chair: Dr. Tony Means The Pharmacology and Cancer Biology Department Graduate Program, known for its excellent research faculty and flexible program, offers interdisciplinary training towards a Ph.D. in Pharmacology and a Ph.D. in Molecular Cancer Biology and Toxicology. Due to the interdisciplinary nature of pharmacology, graduate programs are diverse and flexible. Students take a small core of courses in pharmacology and complete their didactic instruction with courses in areas related to their research including molecular biology, biochemistry, genetics, and cell biology. |
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Stem cells give rise to populations of differentiated cells in an organ specific manner. These cells are attractive targets for pharmaceutical intervention and can be defective in human cancers. This is a confocal image showing gonadal stem cells in different phases of the cell cycle. Mice lacking the gene encoding the Pin1 gene are sterile due to cell cycle defects in these primordial germ cells that lead to a profound decrease in their number. One possible mechanism for this defect is that Pin1 can control the turnover of key phosphorylated cell cycle regulatory proteins such as c-myc. | |
| For further information, contact: Donald McDonnell Director of Graduate Studies Department of Pharmacology and Cancer Biology Duke University Medical Center DUMC 3813 Durham, NC 27710 919-684-6035 |
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